The Centro meets all currently known requirements for a versatile, robust and sensitive microplate luminometer. The selected detector and the proprietary design of the optical sytem guarantee lowest background and negligible crosstalk.

Plate formats

Any opaque microplate in either 96 or 384 well format can be measured. There is no need for any mechanical adjustment just select the plate type in the operating software.

Temperature control

The Centro can be equipped with plate heating for applications where the assay must be measured at elevated and constant temperature such as cell based assays.

Reagent dispensing

3 independently controlled injectors with variable volume give entire freedom in the selection of assay type and assay sequence.
The volume is adjustable from 10 to 100 µl – perfectly fitting the demands for reagent addition into 96 and 384 well plates.
Dispensing can even be performed during a kinetic measurement, e.g. to watch the effects of added agonists / antagonists.
JET injection technology stands for precision and accuracy – better than 99 % and 98 % respectively – and the only reliable way of properly mixing the added reagents.

Shaking

3 modes each with variable speed of the integrated shaker to enhance mixing and optimise sample distribution before measurement in long term kinetics.

Small footprint

The ergonomic design of the LB 960 Centro requires minimal bench space. All the important features are built in making maximum use of available bench space. The reagent injectors are housed within the small footprint, providing the advantage of short tubing and thus a low dead volume.

Preferred Applications

• Cellular luminescence
• Oxidative burst
• Calcium monitoring with Aequorin
• Immunoassays in Clinical Diagnostics
  Acridinium ester, Luminol
• Immunoassays in Research
  Horseradish Peroxidase (HRP),
  Alkaline Phosphatase (ALP) with
  luminescent substrates (e.g. ECL)
  Acridinium ester, Luminol
• Adenylate Kinase assays

For detailed application information and selection of best suited instrument refer to the Centro Selection Guide.

Stacker & Robotic integration

Specially designed for but not restricted to the use in HTS departments of drug discovery companies the robot access module allows for uncomplicated integration of the Centro into any type of lab automation system. Software and hardware easily integrate into existing robotic or liquid handling systems. A barcode reader is available on request for positive plate identification.

The instruments can be used as a stand alone unit or can be integrated into the Berthold BUTLER LB 930 or any other robot system.