CentroLIA, the stand-alone microplate luminometer from Berthold Technologies, is especially designed for luminescence immunoassays.
The use of softkeys with an interactive text display of their associated function makes the CentroLIA an extremely user-friendly, easy-to-use, instrument.

Simple, Intuitive Menus

A large display helps guide the user through all the instrument set up parameters and assay definitions.
The user just follows the screen menus and enters the required parameters for the specific assays. Once the parameters for an assay have been defined the protocols are stored in the instrument memory.
During routine operation, the user selects the required protocol from the “PROTOCOL MANAGEMENT“ menu, then simply load the plate and press “MEASUREMENT“.

• Up to 50 different protocols can be stored. Protocol types are immunometric (ILMA), competitive (LIA), cut-off and raw data. Protocols may be entered via PC or manually.
  
• Automatic performance test with optional test plate
  
• Two point calibration using stored curve or master curve
  
• Flexible definition of wells to be measured
  
• Sequence selection for column or row strip assay
  
• Multiple assays per plate
  
• Shaking: 3 modes, variable amplitude and speed
  
• Full support of kit lot numbers
  
• Storage of assay results allowing off-line reevaluation
  
• Robot integration due to software compatibility and hardware accessibility
  
• PC connection for data output to laboratory information management systems
  
• Sophisticated curve fitting
  
• The curve fitting provides full standardization allowing multiple replicates of standards, totals, Bo´s and NSB´
  
• Storage of standard curves is also possible by manual data entry (master curve), or simply storing the last curve used

Instrument Concept

Detector sensitivity and stability are the result of Berthold Technologies experience with thousands of photon counters.
True photon counting has the benefit that no user parameters need to be set, ensuring the same conditions are used for every measurement during the instrument’s life time. The fast photon counting circuitry provides a dynamic range in excess of six orders of magnitude, which complements the concentration range of the latest assays.
A patented design of the optical system achieves absolute minimization of cross-talk (down to 10⁶, depending on the type of microplate).
96 well plates, 8 well and 12 well strip plates can be measured. Inside the instrument a precision x-y-table ensures exact positioning of the wells with respect to the detector.

The Kit Manufacturers’ Perspective

The CentroLIA is distinguished by it’s exceptionally high sensitivity, thereby allowing clinically significant detection limits with low reagent concentrations. A wide selection of high-quality standardization procedures ensures optimum accuracy and precision in the measurement of assays.
Berthold Technologies world-wide customer service network is available for OEM-partners and users alike so, in the unlikely event of something going wrong, support is available.