The ChemiBIS is an fully automated imaging system for a wide range of chemiluminescent samples or samples stainend with fluorescent and colorimetric (visible) dyes.
The system is equipped with a highly sensitive CCD camera with liquid cooling.

Camera

The ChemiBIS captures the sharpest possible images with precise sample separation - thanks to its powerful CCD camera with high resolution.  
Two different models are available, 2.0 and 3.2 Mpixels.
The high speed zoom lens results in enhanced sensitivity, collecting maximum light from the sample, while maintaining sharp images.
For better accuracy, longer exposure time and minimal dark noise the Deep Liquid Cooling System cools the camera to minimum of -70°C.

Fully Automated

Featuring a motorized zoom, iris and autofocus, the ChemiBIS is a fully automated system.

Dark chamber

The unique dark chamber with an automated UV protection mechanism ensures maximum safety

Illumination

The ChemiBIS is equipped with a built-in transilluminator with dual UV/WL illumination and two interchangeable UV and WL drawers. Automatic Drawer Detection technology indentifies the type of drawer in use and adjusts the software settings accordingly.
The motorized 5-position filter wheel is equipped with 3 filters in 520nm, 580nm and 600nm. A white light epi illumination is installed, a UV epi illlumination can be addded optionally.
The optional HeptaLED system provides illumination of 6 different wavelenghts at 470nm, 500nm, 525nm, 568nm, 588nm and 621nm.


Applications

You can use the ChemisBIS for almost any chemiluminescent, fluorescent or colorimetric application thanks to it's extensive illumination options.

Software

The ChemiBIS will be delivered standardly with two software packages, GelCapture for imaging acquisition and Quant for image analysis.

GelCapture offers complete, automatic control of configuring, capturing, and saving sample images for analysis. GelCapture offers all important image settings adjustable as illumination, focus, brightness, binning and many more. 

The Quant software from TotalLab enables fast and consistent analysis of your gel images with high levels of automation and accuracy.
You can perform a complete analysis with a single click and then refine results afterwards, or step through the different analysis stages giving you complete control at each stage.
Automated lane creation, band detection and background subtraction are all performed without any user intervention for the utmost in analysis consistency.
Molecular weight can be calculated for your bands from the standard marker lane you included on the gel. There are additional tools to adjust band edges and account for band "grimacing" on awkward gels.

Also included with the Quant software are modules for:

• Array, dot / slot blot analysis
• Colony counting
• A toolbox for general image analysis

Specifications

Camera and Optics
 
CCD resolution:2184 x 1510; 3.2M pixels 
                 or 1640 x 12214; 2.0M pixels
Gradation: 16 bit file format
Dynamic range: 4.6 orders of magnitude 
Binning: 1x1, 2x2, 3x3, 4x4, 5x5, 6x6, 7x7, 8x8
Super bright lens: F/0.95
 
Illumination and Darkroom
 
Dark chamber: automated UV protection mechanism 
Emission filters: 5 position filter wheel with 3 filters included as a standard
Illumination modes: Trans-UV, Trans-WL, Epi-WL
                           optional: Epi-UV
Excitation sources: White Light source, 312nm
                           optional: 254nm, 365nm
                           optional: dual UV source
                           optional: Monochromatic LEDs system (Hepta LED System)
Software
 
Image capture: GelCapture, lifetime free upgrade 
Image analysis: Quant for 1D analysis (Total Lab)
                      optional: GelQuant, Phoretix 1D, Phoretix 1D Pro

The MiniBIS and MiniBIS Pro products are available in Germany, The Netherlands, Belgium, Luxemburg, Italy, India, France, Switzerland, UK, Japan and USA.

For other countries please see the DNR Imaging Systems homepage.