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Literature about Mithras LB 940 Multimode Reader

FRET Assay: Gratz et al.(2010):
  A FRET-based microplate assay for human protein kinase CK2, a target in neoplastic disease; Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 25, Number 2, April 2010 , pp. 234-239(6)
Fluorescence: Hantel et al.(2010):
  Anti Insulin-Like Growth Factor I Receptor Immunoliposomes: A Single Formulation Combining Two Anticancer Treatments with Enhanced Therapeutic Efficiency; The Journal of Clinical Endocrinology & Metabolism Vol. 95, No. 2 943-952
ATP Assay: Terhaz et al.(2010):
  Mislocalization of mitochondria and compromised renal function and oxidative stress resistance in Drosophila SesB mutants; Physiol. Genomics 41: 33-41, 2010.
Dual-Luciferase Assay in Arabidopsis: Nakamichi et al.(2010)
  PSEUDO-RESPONSE REGULATORS 9, 7, and 5 Are Transcriptional Repressors in the Arabidopsis Circadian Clock
Dual-Luciferase assay in Arabidopsis: Yamaguchi et al.(2010)
  VND-INTERACTING2, a NAC Domain Transcription Factor, Negatively Regulates Xylem Vessel Formation in Arabidopsis; The Plant Cell 22:1249-1263 (2010)
Absorbance at 405nm: Melin (2010):
  Interaction of Pneumococcal Histidine Triad Proteins with Human Complement; Infection and Immunity, May 2010, p. 2089-2098, Vol. 78, No. 5
Fluorescence: Raaben et al.(2010):
  The Ubiquitin-Proteasome System Plays an Important Role during Various Stages of the Coronavirus Infection Cycle; Journal of Virology, August 2010, p. 7869-7879, Vol. 84, No. 15
Luciferase Assay in Arabidopsis: Albert et al.(2010):
  Arabidopsis thaliana Pattern Recognition Receptors for Bacterial Elongation Factor Tu and Flagellin Can Be Combined to Form Functional Chimeric Receptors; The Journal of Biological Chemistry, 285, 19035-19042
Calcium Assay with Fura-2: Kawasaki et al.(2010):
  Protein Kinase C-induced Phosphorylation of Orai1 Regulates the Intracellular Ca2+ Level via the Store-operated Ca2+ Channel; The Journal of Biological Chemistry, 285, 25720-25730.
Luciferase & beta-Gal Assay: Coyaud et al.(2010):
  Wide diversity of PAX5 alterations in B-ALL: a Groupe Francophone de Cytogénétique Hématologique study; Blood, 15 April 2010, Vol. 115, No. 15, pp. 3089-3097
BRET: Rochdi et al.(2010):
  Functional Characterization of Vasopressin Type 2 Receptor Substitutions (R137H/C/L) Leading to Nephrogenic Diabetes Insipidus and Nephrogenic Syndrome of Inappropriate Antidiuresis: Implications for Treatments; Molecular Pharmacology May 2010 vol. 77 no. 5 836-845
Luciferase Assay in Arabidopsis: Nakamichi et al. (2010):
  PSEUDO-RESPONSE REGULATORS 9, 7, and 5 Are Transcriptional Repressors in the Arabidopsis Circadian Clock; Plant Cell Advance Online Publication 10.1105/tpc.109.072892
BRET: Busillo et al.(2010):
  Site-specific Phosphorylation of CXCR4 Is Dynamically Regulated by Multiple Kinases and Results in Differential Modulation of CXCR4 Signaling; March 5, 2010 The Journal of Biological Chemistry, 285, 7805-7817
Protease Assay with AMC Fluorescence: Hartleben et al. (2010):
  Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice; J Clin Invest. doi:10.1172/JCI39492.
ELISA Assay: Qiao et al. (2009):
  Collagen XVII Participates in Keratinocyte Adhesion to Collagen IV, and in p38MAPK-Dependent Migration and Cell SignalingCOL17-Deficient Keratinocytes Decreased Migration; Journal of Investigative Dermatology 129, 2288-2295 (September 2009)
BRET: Kamal et al.(2009):
 
Improved donor/acceptor BRET couples for monitoring beta-arrestin recruitment to G protein-coupled receptors; Biotechnology Journal
Volume 4 Issue 9, Pages 1337 - 1344
Calcium assay with Aequorin: Poutrain et al. (2009):
  Two distinct intracellular Ca2+-release components act in opposite ways in the regulation of the auxin-dependent MIA biosynthesis in Catharanthus roseus cells; Journal of Experimental Botany 2009 60(4):1387-1398
Fluorescence Polarisation: Nicholls et al.(2009)
  Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition; PNAS March 10, 2009 vol. 106 no. 10 3889-3894
Dual-Glo Luciferase Assay: Sakai et al.(2009):
  The importance of heterogeneous nuclear ribonucleoprotein K on Cytochrome P450 2D2 gene regulation: its binding is reduced in Dark Agouti rats; Drug Metabolism and Disposition DOI: 10.1124/dmd.109.027284
Caspase Assay: Schnitzer et al:(2009)
  Hypoxia Enhances Sphingosine Kinase 2 Activity and Provokes Sphingosine-1-Phosphate-Mediated Chemoresistance in A549 Lung Cancer Cells; Mol Cancer Res March 2009 7, 393
Taxane ELISA: Ottaggio et al.(2010):
  Taxanes from Shells and Leaves of Corylus avellana; J. Nat. Prod., 2008, 71 (1), pp 58–60
BRET: Vrecl et al. (2009):
  β-Arrestin-Based Bret2 Screening Assay for the "Non"-β-Arrestin Binding CB1 Receptor; Journal of Biomolecular Screening, Vol. 14, No. 4, 371-380 (2009)
HTRF® & BRET: Schroeder et al.(2008):
   The C-terminal tail of CRTH2 is a key molecular determinant that constrains GalphaI- and downstream-signaling cascade activation; J. Biol. Chem 10.1074/jbc.M806867200
BRET: Langane et al.(2008):
  CXCR4 dimerization and β-arrestin–mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome; Blood, 1 July 2008, Vol. 112, No. 1, pp. 34-44
Fluorescence Polarisation: Burgevin et al.(2008):
  A Detailed Analysis of the Murine TAP Transporter Substrate Specificity; PLoS ONE, 1 June 2008, Volume 3, Issue 6

DLR: Harmsen et al.(2008):
  Comparison of Two Immortalized Human Cell Lines to Study Nuclear Receptor-Mediated CYP3A4 Induction; Drug Metabolism and Disposition, DOI: 10.1124/dmd.107.017335
BRET: Perroy et al.(2008):
  Direct Interaction Enables Cross-talk between Ionotropic and Group I Metabotropic Glutamate Receptors; J. Biol. Chem., Vol. 283, Issue 11, 6799-6805, March 14, 2008
BRET: Jorgensen et al.(2008):
  Characterization of G-Protein Coupled Receptor Kinase Interaction with the Neurokinin-1 Receptor Using Bioluminescence Resonance Energy Transfer; Mol Pharmacol 73:349-358, 2008
Fluorescence: Roccaro et al.(2008):
  Dual targeting of the proteasome regulates survival and homing in Waldenstrom's Macroglobulinemia; Blood DOI 10.1182/blood-2007-11-120972
Cytotoxicity Assay: Raftery et al.(2008):
  Inhibition of CD1 Antigen Presentation by Human Cytomegalovirus; J. Virol. doi:10.1128/JVI.01447-07
Luciferase Assay: Adamson et al.(2008):
  Human Prolactin Gene Promoter Regulation by Estrogen: Convergence with Tumor Necrosis Factor-alpha-Signaling; Endocrinology Vol. 149, No. 2 687-694
BRET: Coulon et al.(2008):
  Subcellular Imaging of Dynamic Protein Interactions by Bioluminescence Resonance Energy Transfer; Biophysical Journal 94:1001-1009 (2008)
Dual-Luciferase Assay: Chen et al.(2008):
  Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity; RNA (2008), 14:263-274
BRET: Feng et al.(2008):
  Cytoplasmic terminus of a vacuolar type proton pump accessory subunit Ac45 is required for proper interaction with V0 domain subunits and efficient osteoclastic bone resorption; J. Biol. Chem, 10.1074/jbc.M709712200
ROS assay with DCFDA fluorescence: Schmidt et al.(2008):
  The uraemic toxin phenylacetic acid increases the formation of reactive oxygen species in vascular smooth muscle cells; Nephrology Dialysis Transplantation 2008 23(1):65-71
BRET: Masri et al.(2008):
  Antagonism of dopamine D2 receptor/β-arrestin 2 interaction is a common property of clinically effective antipsychotics; PNAS September 9, 2008 vol. 105 no. 36 13656-13661
Chemiluminescence: Nakashima et al.(2008):
  A Prodigiosin Analogue Inactivates NADPH Oxidase in Macrophage Cells by Inhibiting Assembly of p47phox and Rac; Journal of Biochemistry 2008 143(1):107-115
Caspase Assays: Christenson et al.(2008):
  Serum amyloid A inhibits apoptosis of human neutrophils via a P2X7-sensitive pathway independent of formyl peptide receptor-like 1; Journal of Leukocyte Biology 2008; 83:139-148
Chemiluminescence: Ziegler et al.(2008):
  Dehydroepiandrosterone Induces a Neuroendocrine Phenotype in Nerve Growth Factor-Stimulated Chromaffin Pheochromocytoma PC12 Cells; Endocrinology Vol. 149, No. 1 320-328
Calcium Assay with Fura: Harzenetter et al.(2007):
  Negative Regulation of TLR Responses by the Neuropeptide CGRP Is Mediated by the Transcriptional Repressor ICER; The Journal of Immunology, 2007, 179: 607-615
BRET: Héroux et al.(2007):
  Functional Calcitonin Gene-related Peptide Receptors Are Formed by the Asymmetric Assembly of a Calcitonin Receptor-like Receptor Homo-oligomer and a Monomer of Receptor Activity-modifying Protein-1; J. Biol. Chem., Vol. 282, Issue 43, 31610-31620, October 26, 2007
Fluorescence Adhesion Assay: Vallet et al.(2007):
  MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclastis; Blood, 15 November 2007, Vol. 110, No. 10, pp. 3744-3752
Luciferase Assay: Diaz et al.(2007):
  p160 Myb-Binding Protein Interacts with Prep1 and Inhibits Its Transcriptional Activity; Molecular and Cellular Biology, November 2007, p. 7981-7990, Vol. 27, No. 22
BRET: Hamdan et al.(2007):
  Unraveling G Protein-coupled Receptor Endocytosis Pathways Using Real-time Monitoring of Agonist-promoted Interaction between beta-Arrestins and AP-2; J. Biol. Chem., Vol. 282, Issue 40, 29089-29100, October 5, 2007
Fluorescence: Patschan et al.(2007):
  MAPPING MECHANISMS AND CHARTING TIME COURSE OF PREMATURE SENESCENCE AND APOPTOSIS: LYSOSOMAL DYSFUNCTION AND GANGLIOSIDE ACCUMULATION IN ENDOTHELIAL CELLS; Am J Physiol Renal Physiol October 10, 2007
Cellular Chemiluminescence: Thoren et al.(2007):
  The CD16–/CD56bright Subset of NK Cells Is Resistant to Oxidant-Induced Cell Death; The Journal of Immunology, 2007, 179: 781-785.
Phospholipase D Assay with Amplex Red: Zeniou-Meyer et al. (2007):
  Phospholipase D1 Production of Phosphatidic Acid at the Plasma Membrane Promotes Exocytosis of Large Dense-core Granules at a Late Stage; J. Biol. Chem., Vol. 282, Issue 30, 21746-21757, July 27, 2007
BRET: Quaynor et al.(2007):
  Expression of a Functional G Protein-Coupled Receptor 54-Kisspeptin Autoregulatory System in Hypothalamic Gonadotropin-Releasing Hormone Neurons; Molecular Endocrinology 21 (12): 3062-3070
BRET: Tan et al.(2007):
  Monitoring Interactions between Receptor Tyrosine Kinases and Their Downstream Effector Proteins in Living Cells Using Bioluminescence Resonance Energy Transfer; Mol Pharmacol 72:1440-1446, 2007
Fluorescence: Catalano et al.(2007):
  Valproic acid enhances tubulin acetylation and apoptotic activity of paclitaxel on anaplastic thyroid cancer cell lines; Endocrine-Related Cancer 14 (3) 839-845
Apoptosis with AFC: Lee at al.(2007):
  Cadmium-induced ceramide formation triggers calpain-dependent apoptosis in cultured kidney proximal tubule cells; Am J Physiol Cell Physiol 293: C839-C847, 2007
Luciferase Assay: Fonseca et al.(2007):
  A Polymorphism in the CTGF Promoter Region Associated with Systemic Sclerosis; The New England Journal of Medicine, Sep 2007, 357: 1210 - 1220
Cellular Chemiluminescence: Ziegler et al.(2007):
  Dehydroepiandrosterone (DHEA) induces a neuroendocrine phenotype in nerve growth factor (NGF)-stimulated chromaffin pheochromocytoma PC12 cells; Endocrinology, doi:10.1210/en.2007-0645
Luminescence: Zhou et al.(2007):
  Yeast screens show aromatic residues at the end of the sixth helix anchor transient receptor potential channel gate; PNAS, September 25, 2007, vol. 104, no. 39, 15555-15559
Fluorescence: Wei et al.(2007):
  Enhanced Lysosomal Pathology Caused by beta-Synuclein Mutants Linked to Dementia with Lewy Bodies; J. Biol. Chem., Vol. 282, Issue 39, 28904-28914, September 28, 2007
Dual-Luciferase Assay: Gradisar et al.(2007):
  MD-2 as the target of curcumin in the inhibition of response to LPS; Journal of Leukocyte Biology. 2007;82:968-974
Luminescence: Bettenbrock et al.(2007):
  Correlation between Growth Rates, EIIACrr Phosphorylation, and Intracellular Cyclic AMP Levels in Escherichia coli K-12; Journal of Bacteriology, October 2007, p. 6891-6900, Vol. 189, No. 19
BRET: Coulon et al.(2007):
  SUBCELLULAR IMAGING OF DYNAMIC PROTEIN INTERACTIONS BY BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; Biophys. J.; doi:10.1529/biophysj.107.117275
BRET: Sohy et al.(2007):
  Allosteric Transinhibition by Specific Antagonists in CCR2/CXCR4 Heterodimers; J. Biol. Chem., Vol. 282, Issue 41, 30062-30069, October 12, 2007
BRET: Jorgensen et al.(2007):
  Characterization of G-Protein Coupled Receptor Kinase Interaction with the NK-1 Receptor Using BRET, Molecular Pharmacology November 6, 2007 doi:10.1124/mol.107.038877
Luciferase Assay: Takeda et al.(2007):
  A Human Lung Carcinoma Cell Line Supports Efficient Measles Virus Growth and Syncytium Formation via a SLAM- and CD46-Independent Mechanism; Journal of Virology, November 2007, p. 12091-12096, Vol. 81, No. 21
BRET: Turu et al.(2007):
  The Role of Diacylglycerol Lipase in Constitutive and Angiotensin AT1 Receptor-stimulated Cannabinoid CB1 Receptor Activity; J. Biol. Chem., Vol. 282, Issue 11, 7753-7757
Dual-Luciferase-Assay: Haim et al.(2007):
  Time Frames for Neutralization during the Human Immunodeficiency Virus Type 1 Entry Phase, as Monitored in Synchronously Infected Cell Cultures; Journal of Virology, April 2007, p. 3525-3534, Vol. 81, No. 7
BRET: Lupien et al.(2007):
  Raloxifene and ICI182,780 Increase Estrogen Receptor- Association with a Nuclear Compartment via Overlapping Sets of Hydrophobic Amino Acids in Activation Function 2 Helix 12; Molecular Endocrinology 21 (4): 797-816
Luminescence Immunoassay: Bogan et al.(2007):
  Constitutive Steroidogenesis in Ovine Large Luteal Cells May Be Mediated by Tonically Active Protein Kinase A; Biol Reprod 2007, 10.1095/biolreprod.106.059618
Luciferase Assay: Willige et al.(2007):
  The DELLA Domain of GA INSENSITIVE Mediates the Interaction with the GA INSENSITIVE DWARF1A Gibberellin Receptor of Arabidopsis; The Plant Cell 10.1105/tpc.107.051441
Chemiluminescence: Tahara et al.(2007):
  Altered Interaction of the Matrix Protein with the Cytoplasmic Tail of Hemagglutinin Modulates Measles Virus Growth by Affecting Virus Assembly and Cell-Cell Fusion; J. Virol. doi:10.1128/JVI.00248-07
Secretory transport with rhodamine 123 fluorescence: Yamagata et al.(2007):
 

Improvement of the Oral Drug Absorption of Topotecan through the Inhibition of Intestinal Xenobiotic Efflux Transporter, Breast Cancer Resistance Protein (BCRP), by Excipients;
J. Biol. Chem., Vol. 282, Issue 8, 5736-5748
BRET: Fessart et al.(2007):
  Src-dependent phosphorylation of 2-adaptin dissociates the -arrestin-AP-2 complex; Journal of Cell Science doi: 10.1242/jcs.03444
NADH Fluorescence: Ueo et al. (2007):
  Cl--Dependent up-regulation of human organic anion transporters: Different effects on transport kinetics between hOAT1 and hOAT3; Am J Physiol Renal Physiol, April 11, 2007
Enzyme activity of Proteasome and Cathepsin B: Fujita et al.(2007):
  a-Synuclein Stimulates Differentiation of Osteosarcoma Cells: RELEVANCE TO DOWN-REGULATION OF PROTEASOME ACTIVITY; J. Biol. Chem., Vol. 282, Issue 8, 5736-5748
BRET: Berchiche et al.(2007):
  Direct Assessment of CXCR4 Mutant Conformations Reveals Complex Link between Receptor Structure and Gi Activation; J. Biol. Chem., Vol. 282, Issue 8, 5111-5115, February 23, 2007
BRET: Jorgensen et al.(2007):
  Oxyntomodulin differentially affects Glucagon-Like Peptide-1 receptor beta-arrestin recruitment and signaling through G-alpha-s; Journal of Pharmacology And Experimental Therapeutics, DOI: 10.1124/jpet.107.120006
Reactive oxygen species (cellular luminescence) + DHR fluorescence: Mauch et al.(2007):
  Chronic Granulomatous Disease (CGD) and Complete Myeloperoxidase Deficiency Both Yield Strongly Reduced Dihydrorhodamine 123 Test Signals but Can Be Easily Discerned in Routine Testing for CGD; Clinical Chemistry clinchem.2006.083444v1, 2007
BRET: Elster et al.(2007):
  Bioluminescence Resonance Energy Transfer as a Screening Assay: Focus on Partial and Inverse Agonism; Journal of Biomolecular Screening, Vol. 12, No. 1, 41-49 (2007)
Cytotoxicity + Absorbance: Sicard et al.(2007):
  Age-dependent regulation of chromaffin cell proliferation by growth factors, dehydroepiandrosterone (DHEA), and DHEA sulfate; PNAS, vol. 104, no. 6 , 2007-2012 

 
BRET: Holst et al.(2007):
  GPR39 Signaling Is Stimulated by Zinc Ions But Not by Obestatin; Endocrinology Vol. 148, No. 1 13-20
Dual-Luciferase-Assay: Haim et al.(2007):
  Time Frames of Neutralization During the HIV-1 Entry Phase, as Monitored in Synchronously Infected Cell Cultures; J. Virol. doi:10.1128/JVI.02293-06
BRET: Schiffer et a.(2007):
  Pharmacology and Signaling Properties of Epidermal Growth Factor Receptor Isoforms Studied by Bioluminescence Resonance Energy Transfer; Mol Pharmacol 71:508-518, 2007
BRET: Turu et al.(2007):
  The role of diacylgycerol lipase in constitutive and angiotensin AT1 receptor-stimulated cannabinoid CB1 receptor activity; J. Biol. Chem, 10.1074/jbc.C600318200
BRET + Luciferase Assay + ELISA: AYOUB et al.(2007):
  Real-time analysis of agonist-induced activation of protease-activated receptor 1/Gi1 protein complex measured by BRET in living cells; Molecular Pharmacology DOI: 10.1124/mol.106.030304
Chemiluminescence with Acridinium Ester: Adamczyk et al. (2006):
  Choline Concentration in Normal Blood Donor and Cardiac Troponin–Positive Plasma Samples; Clinical Chemistry 52: 2123-2124, 2006
Dual-Luciferase-Assay: Mancek-Keber et al. (2006):
  Structural similarity between the hydrophobic fluorescent probe and lipid A as a ligand of MD-2; The FASEB Journal. 2006;20:1836-1842
Fluorescence: Reiter et al. (2006):
  TRPV4-mediated regulation of epithelial permeability; The FASEB Journal. 2006;20:1802-1812
BRET: Holst et al. (2006):
  GPR39 signaling is stimulated by zinc ions but not by obestatin; Endocrinology, doi:10.1210/en.2006-0933
Luminescence: Osaki et al. (2006):
  Mutation of luxS affects motility and infectivity of Helicobacter pylori in gastric mucosa of a Mongolian gerbil model; J Med Microbiol 55 (2006), 1477-1485
BRET: Schiffer at al. (2006):
  Pharmacology and signaling properties of EGFR isoforms studied by Bioluminescence Resonance Energy Transfer (BRET); Molecular Pharmacology, DOI: 10.1124/mol.106.027656
Luciferase-Assay: Milliat et al. (2006):
  Influence of Endothelial Cells on Vascular Smooth Muscle Cells Phenotype after Irradiation: Implication in Radiation-Induced Vascular Damages; American Journal of Pathology. 2006;169:1484-1495
BRET: Mangmool et al. (2006):
  Clathrin Required for phosphorylation and internalization of 2-adrenergic receptor by G protein-coupled receptor kinase 2 (GRK2); J. Biol. Chem, 10.1074/jbc.M602832200
BRET: Poulsen et al. (2006):
  Dimerization of ADAR2 is mediated by the double-stranded RNA binding domain; RNA (2006), 12:1350-1360
FRET: Nikolaev et al. (2006):
  Molecular basis of partial agonism at the neurotransmitter alpha2A-adrenergic receptor and Gi-protein heterotrimer; J. Biol. Chem, 10.1074/jbc.M603266200
Proteasome Activity by MCA Fluorescence: Hubert-Buron et al. (2006):
  Glutamine Pretreatment Reduces IL-8 Production in Human Intestinal Epithelial Cells by Limiting IB Ubiquitination; The Journal of Nutrition, 136:1461-1465, June 2006
Luciferase-Assay: Galmiche et al. (2006):
  The expression of aromatase in gonadotropes is regulated by estradiol and GnRH in a manner that differs from the regulation of LH; Endocrinology, doi:10.1210/en.2005-1650
Luciferase Assay: Nirula et al. (2006):
  Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4; The Journal of Experimental Medicine, doi:10.1084/jem.20051715
Chemiluminescence, Reporter Assay, Fluorescence with eGFP: Takeda et al. (2006):
  Generation of Measles Virus with a Segmented RNA Genome; Journal of Virology, May 2006, p. 4242-4248, Vol. 80, No. 9
ATP determination: Jacquard et al. (2006):
  Brain mitochondrial defects amplify intracellular [Ca2+] rise and neurodegeneration but not Ca2+ entry during NMDA receptor activation; The FASEB Journal. 2006;20:1021-1023
Luciferase Assay in plants: Calderon-Villalobos et al. (2006):
  LucTrap Vectors Are Tools to Generate Luciferase Fusions for the Quantification of Transcript and Protein Abundance in Vivo; Plant Physiology 141:3-14 (2006)
Dual-Luciferase-Assay: Fujimura et al. (2006):
  A selective peroxisome proliferator-activated receptor  modulator with distinct fat cell regulation properties; Journal of Pharmacology And Experimental Therapeutics, DOI: 10.1124/jpet.106.102459
Fluorescence Measurements of YFP expression: Burstein et al. (2006):
  Characterization of the Mas-related gene family: structural and functional conservation of human and rhesus MrgX receptors; British Journal of Pharmacology (2006) 147, 73–82
Chemiluminescence in liver tissues (Reactive Oxygen Species): Katzenellenbogen et al. (2006):
  Multiple Adaptive Mechanisms to Chronic Liver Disease Revealed at Early Stages of Liver Carcinogenesis in the Mdr2-Knockout Mice; Cancer Research 66, 4001-4010
BRET: Sirokmány et al. (2006):
  Sec14 Homology Domain Targets p50RhoGAP to Endosomes and Provides a Link between Rab and Rho GTPases; J. Biol. Chem., Vol. 281, Issue 9, 6096-6105
BRET: Qazi et al. (2006):
  Ligand-Independent Homo- and Hetero-Dimerization of Human Prolactin Receptor Variants: Inhibitory Action of the Short Forms by Heterodimerization; Molecular Endocrinology, doi:10.1210/me.2005-0291
SNP fluorescence in 1536 well: Okamoto et al. (2006):
  Simple SNP typing assay using a base-discriminating fluorescent probe; Mol. BioSyst., 2006, 2, 122 - 127
BRET: Mathiesen et al. (2006):
  On the mechanism of interaction of potent, surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2; Molecular Pharmacology, DOI: 10.1124/mol.105.017681
BRET: Springael et al. (2006):
  Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers; Molecular Pharmacology, DOI: 10.1124/mol.105.019414
Luciferase Assay: Friedrichsen et al. (2006):
  Tumor Necrosis Factor- Activates the Human Prolactin Gene Promoter via Nuclear Factor-B Signaling; Endocrinology Vol. 147, No. 2 773-781
BRET: Storez et al. (2005):
  Homo- and Hetero-oligomerization of beta-Arrestins in Living Cells; J. Biol. Chem., Vol. 280, Issue 48, 40210-40215
Cell Invasion Assay with CyQuantGR Dye: Levenson et al. (2005):
  MCT-1 Oncogene Contributes to Increased In vivo Tumorigenicity of MCF7 Cells by Promotion of Angiogenesis and Inhibition of Apoptosis; Cancer Research 65, 10651-10656, December 1, 2005
Dual-Luciferase-Assay: FUJINO et al. (2005):
  Spermatogonial Cell-mediated Activation of An IB-independent NF-B Pathway in Sertoli Cells Induces Transcription of the Lipocalin-2 Gene; Molecular Endocrinology, doi:10.1210/me.2005-0423
Luciferase Assay: Friedrichsen et al. (2005):
  TNF-alpha activates the human prolactin gene promoter via NF-kB signaling; Endocrinology, doi:10.1210/en.2005-0967
PIP3 dependent GFP Fluorescence: Várnai et al. (2005):
  Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3,4,5)P3 suggest their interaction with protein binding partners; Journal of Cell Science 118, 4879-4888 (2005)
Yu et al. (2005):
  A 96-Well Surrogate Survival Assay Coupled with a Special Short Interfering RNA Vector for Assessing Cancer Gene Targets with Enhanced Signal/Noise Ratio and Its Utility in HTS for Cancer Therapeutic Targets; ASSAY and Drug Development Technologies. 2005, 3(4): 401-411
Dual-Luciferase-Assay: Yoshimoto et al. (2005):
  Regulation of ocular lens development by Smad-interacting protein 1 involving Foxe3 activation; Development 132, 4437-4448 (2005)
BRET: Huttenrauch et al. (2005):
  G protein-coupled receptor kinases promote phosphorylation and -arrestin-mediated internalization of CCR5 homo- and hetero-oligomers; J. Biol. Chem, 10.1074/jbc.M500535200
Calcium Assay with Fluo-3 AM: Càrdenas et al. (2005):
 

Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation; Journal of Cell Science 118, 3131-3140 (2005)
BRET: Hamdan et al. (2005):
  High-Throughput Screening of G Protein-Coupled Receptor Antagonists Using a Bioluminescence Resonance Energy Transfer 1-Based ß-Arrestin2 Recruitment Assay; Journal of Biomolecular Screening, Vol. 10, No. 5, 463-475 (2005)
Dual-Luciferase-Assay: Schneider et al. (2005):
  The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis; J. Clin. Invest., doi: 10.1172/JCI23559
BRET: Mathiesen et al. (2005):
  Identification of indole derivatives exclusively interfering with a G protein-independent signaling pathway of the prostaglandin D2 receptor CRTH2; Molecular Pharmacology DOI: 10.1124/mol.104.010520
BRET: Holst et al. (2005):
  Non-peptide and Peptide Growth Hormone Secretagogues Act both as Ghrelin receptor Agonist and as Positive or Negative Allosteric Modulators of Ghrelin Signaling; Molecular Endocrinology, doi:10.1210/me.2005-0059
Nucleotid Exchange Assay: Joseph and Norris (2005):
  Substrate specificity and recognition is conferred by the PH domain of the Dbl family guanine nucleotide exchange factor P-Rex2; J. Biol. Chem, 10.1074/jbc.M412495200
AmplexRed Phospholipase D Assay: Vitale et al. (2005):
  The small GTPase RalA controls exocytosis of large dense core secretory granules by interacting with ARF6-dependent PLD1; J. Biol. Chem, 10.1074/jbc.M413748200
Luciferase Assay: Maruyama-Nakashita et al. (2005):
  Identification of a novel cis-acting element conferring sulfur deficiency response in Arabidopsis roots; The Plant Journal 42 (3), 305–314.
Luciferase Assay in plants: Dohmann et al. (2005):
  Loss of the CONSTITUTIVE PHOTOMORPHOGENIC9 Signalosome Subunit 5 Is Sufficient to Cause the cop/det/fus Mutant Phenotype in Arabidopsis; The Plant Cell, Published on May 27, 2005; 10.1105/tpc.105.032870
BRET + cAMP HitHunter Assay: Wilson et al. (2005):
  THE CXCR1 AND CXCR2 RECEPTORS FORM CONSTITUTIVE HOMO AND HETERO-DIMERS SELECTIVELY AND WITH EQUAL APPARENT AFFINITIES; J. Biol. Chem, 10.1074/jbc.M413475200
Aequorine Calcium-Assay: Rogers et al. (2005):
  Visualization of local Ca2+ dynamics with genetically encoded bioluminescent reporters; European Journal of Neuroscience 21 (3), 597–610
Akashi et al. (2005):
  Escape from the interferon response associated with RNA interference using vectors that encode long modified hairpin-RNA; Mol. BioSyst., 2005, 1, 382 - 390
BRET: Percherancier et al. (2005):
  Bioluminescence Resonance Energy Transfer Reveals Ligand-induced Conformational Changes in CXCR4 Homo- and Heterodimers; J. Biol. Chem., Vol. 280, Issue 11, 9895-9903
BRET: Charest et el. (2005):
  Monitoring agonist-promoted conformational changes of -arrestin in living cells by intramolecular BRET; EMBO reports 6, 4, 334–340 (2005)
BRET: Galés et al. (2005):
  Real-time monitoring of receptor and G-protein interactions in living cells; Nature Methods 2, 177 - 184 (2005)
FITC-Albumin Permeability Assay + ELISA: Irwin et al. (2005):
  Direct ANP inhibition of hypoxia-induced inflammatory pathways in pulmonary microvascular and macrovascular endothelial monolayers; Am J Physiol Lung Cell Mol Physiol 288 (5): L849
Luciferase Assay: Tanaka et al. (2005):
  A novel NF-B inhibitor, IMD-0354, suppresses neoplastic proliferation of human mast cells with constitutively activated c-kit receptors; Blood, Vol. 105, No. 6, pp. 2324-2331
BRET: Kostenis et al. (2005):
  G-Protein-Coupled Receptor Mas Is a Physiological Antagonist of the Angiotensin II Type 1 Receptor; Circulation 2005;111:1806
Tait el al. (2005):
  Disruption of quorum sensing in seawater abolishes attraction of zoospores of the green alga Ulva to bacterial biofilms; Environmental Microbiology 7 (2), 229–240
BRET: Jorgensen et al. (2005):
  Characterization of Glucagon-Like Peptide-1 Receptor ß-Arrestin 2 Interaction: A High-Affinity Receptor Phenotype; Molecular Endocrinology 19 (3): 812-823
Luciferase Assay: Nowak et al. (2005):
  Insulin-Mediated Down-Regulation of Apolipoprotein A5 Gene Expression through the Phosphatidylinositol 3-Kinase Pathway: Role of Upstream Stimulatory Factor; Molecular and Cellular Biology, February 2005, p. 1537-1548, Vol. 25, No. 4
Luciferase Assay: Salah et al. (2005):
  Identification of a novel functional androgen response element within hPar1 promoter: implications to prostate cancer progression; FASEB Journal 2005;19:62-72
BRET + Aequorine Calcium Assay: El-Asmar et al. (2005):
  Evidence for Negative Binding Cooperativity within CCR5-CCR2b Heterodimers; Mol Pharmacol 67:460-469, 2005
BRET: Perroy et al. (2004):
  Real-time monitoring of ubiquitination in living cells by BRET; Nature Methods 1, 203 - 208 (2004)
BRET: Vrecl al. (2004):
  Development of a BRET2 Screening Assay Using ß-Arrestin 2 Mutants; Journal of Biomolecular Screening, Vol. 9, No. 4, 322-333 (2004)
BRET: Heding et al. (2004):
  Use of the BRET 7TM receptor/-arrestin assay in drug discovery and screening; Future Drugs Vol. 4, No. 3, Pages 403-411
DNA quantification, Luciferase Assay: Little et al. (2004):
  Poly-amino ester-containing microparticles enhance the activity of nonviral genetic vaccines; PNAS 101 (26): 9534
Grovender et al. (2004):
  Single-chain antibody fragment-based adsorbent for the extracorporeal removal of 2-microglobulin; Kidney Int. 2004 Jan;65(1):310-22.
Aequorine Calcium Assay: Radford et al. (2004):
  Functional characterisation of the Anopheles leucokinins and their cognate G-protein coupled receptor; Journal of Experimental Biology 207, 4573-4586 (2004)
BRET: Ramsay et al. (2004): ;
  High-Affinity Interactions between Human 1A-Adrenoceptor C-Terminal Splice Variants Produce Homo- and Heterodimers but Do Not Generate the 1L-Adrenoceptor; Mol Pharmacol 66:228-239, 2004
Absorbance: Pollock et al. (2004):
  Conservation of capa peptide-induced nitric oxide signalling in Diptera; Journal of Experimental Biology 207, 4135-4145 (2004)
Cytotoxicity and Cell Proliferation: Gaunitz et al. (2003):
  HTS compatible assay for antioxidative agents using primary cultured hepatocytes; Assay Drug Technol. 2003 Jun;1(3):469-77
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